Patient-reported outcomes improve with etanercept plus methotrexate in active early rheumatoid arthritis and the improvement is strongly associated with remission : the COMET trial.
Kekow, J;Moots, R J;Emery, P;Durez, Patrick;Sato, R;et.al.
To compare the effects of etanercept (ETN) 50 mg once weekly plus methotrexate (MTX) versus MTX alone on patient-reported outcomes (PROs) and the relationship between remission and PRO improvement.
Kekow, J., Moots, R. J., Emery, P., Durez, P., Koenig, A., Singh, A., Pedersen, R., Robertson, D., Freundlich, B., & Sato, R. (2010). Patient-reported outcomes improve with etanercept plus methotrexate in active early rheumatoid arthritis and the improvement is strongly associated with remission : the COMET trial. Annals of the Rheumatic Diseases. https://doi.org/10.1136/ard.2008.102509