One step TNM staging of patients with high risk prostate cancer using MRI
(2016)
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- Authors
- Supervisors
- Lecouvet, Frédéric
- Abstract
- A review of the literature on the use of whole body MRI (WBMRI) for the detection of bone metastasis highlights the recent advances of the technique and puts it in the spotlight as a sensitive, specific, non-irradiating and economically sound tool for cancer staging. The important heterogeneity in WBMRI protocols and the long acquisition times resulting from the addition of multiple anatomic sequences in different planes, motivated the first study. This study validates a 3D sequence as substitute to the multiple anatomic sequences used until now for node and bone staging in prostate cancer. Starting from the established role of multiparametric MRI of the prostate for local staging and from the value of WBMRI for the detection of bone and node metastasis, a second study investigates the feasibility of a complete TNM staging of prostate cancer in a single MRI session. This second study relies on the development of an imaging protocol, combining a multiparametric MRI (for T or local staging) and a WBMRI (for M or bone, and N or node staging), allowing for a comprehensive TNM staging of prostate cancer in less than an hour.
- Affiliations
Citations
Pasoglou, V. (2016). One step TNM staging of patients with high risk prostate cancer using MRI. https://hdl.handle.net/2078.5/184112