Successive treatment with cyclosporine and infliximab in steroid-refractory ulcerative colitis.
(2011) The American journal of gastroenterology — Vol. 106, n° 4, p. 771-777 (2011)
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- Abstract
- Rescue therapy with either cyclosporine (CYS) or infliximab (IFX) is an effective option in patients with intravenous steroid-refractory attacks of ulcerative colitis (UC). In patients who fail, colectomy is usually recommended, but a second-line rescue therapy with IFX or CYS is an alternative. The aims of this study were to investigate the efficacy and tolerance of IFX and CYS as a second-line rescue therapy in steroid-refractory UC or indeterminate colitis (IC) unsuccessfully treated with CYS or IFX.
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Leblanc, S., Allez, M., Seksik, P., Flourié, B., Peeters, H., Dupas, J. L., Bouguen, G., Peyrin-Biroulet, L., Duclos, B., Bourreille, A., Dewit, O., Bouhnik, Y., Michetti, P., Chaussade, S., Saussure, P., Mary, J. Y., Colombel, J. F., & Lémann, M. (2011). Successive treatment with cyclosporine and infliximab in steroid-refractory ulcerative colitis. The American journal of gastroenterology, 106(4), 771-777. https://doi.org/10.1038/ajg.2011.62 (Original work published 2011)