Current practice in clinical thrombosis and hemostasis
(2011) The Journal of Coagulation Disorders — Vol. 3, n° 1, p. 9-13 (2011)
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- Abstract
- Clinical thrombosis and hemostasis is emerging as a growing subspecialty area characterized by an increasing interaction between clinical and laboratory medicine and many other disciplines. The impact of these changes on the activity and workload of specialized hemostasis and thrombosis clinics has so far not been analyzed. Reasons for referral, final diagnoses, and results of hemostatic evaluations in all out-patients referred over a 24-month period to the Haemostasis and Thrombosis Unit and Haemophilia Center of the Cliniques Universitaires Saint-Luc, Brussels, were reviewed. In total, 4502 out-patient consultations were analyzed representing 23% of the total activity of the hematology division. A majority of patients (63.6%) were referred for venous or arterial thromboembolic diseases including venous thromboembolic events (30.8%), thrombophilia screening for complicated pregnancy and monitoring of anticoagulation during pregnancy (12.2%), primary or secondary venous insufficiency (10.9%), arterial thrombosis (6.3%), or family screening for thrombophilia (3.4%). A smaller group (23.7%) was referred for evaluation of bleeding symptoms (14.2%) or follow-up of inherited bleeding disorders (hemophilia, 7.0% and von Willebrand disease, 1.3%). A thrombophilic trait was found among 28% of patients referred for thrombophilia testing. Among patients with bleeding symptoms, a biological abnormality was found in 32.6% of patients using routine tests. Since the conclusions of this study largely reflect the local set-up and patterns of referral to a single thrombosis and hemostasis clinic, they cannot be generalized and extrapolated to other centers. They, however, provide valuable and original information on the wide spectrum of clinical hemostasis and thrombosis and highlight the competences and skills needed by specialists in coagulation disorders.
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Lambert, C., & Hermans, C. (2011). Current practice in clinical thrombosis and hemostasis. The Journal of Coagulation Disorders, 3(1), 9-13. https://hdl.handle.net/2078.5/187975 (Original work published 2011)