During the last two decades, biodegradable metals have been studied in an effort to replace permanent intravascular stents. The material with ideal degradation rate and behavior, mechanical properties, and biocompatibility has not yet been found. We evaluated the in vitro degradation and surface properties and the in vivo behavior of different biodegradable metals using microfocus X-ray computed tomography (microCT) and contrast-enhanced microCT (CECT). Wires were used to mimic a single stent strut.