Increased uptake of indium-111 pentetreotide up to 10 years after external thoracic irradiation: report of two cases.

Stoffel, M.;Jamar, François;Donckier, Julian;Hainaut, Philippe;Pauwels, Stanislas;et.al.
(1996) European journal of nuclear medicine — Vol. 23, n° 6, p. 723-726 (1996)

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Authors
  • Stoffel, M.
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  • Hainaut, PhilippeUCLouvain
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  • De Coster, PatrickUCLouvain
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  • Beckers, ChristianUCLouvain
    Author
  • Pauwels, StanislasUCLouvain
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Abstract
Indium-111 pentetreotide scintigraphy was performed in two patients for the localization of recurrent medullary thyroid carcinoma treated by surgery and external radiotherapy 1 and 10 years earlier. A marked uptake of the radiopharmaceutical was demonstrated in the lung areas that had been irradiated. These cases strongly suggest that this uptake is related to pulmonary fibrosis, a well-known complication of radiotherapy, even long after the irradiation. Therefore, attention must be paid to the avoidance of false-positive interpretation of somatostatin receptor scintigraphy in patients previously treated by radiotherapy.
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Stoffel, M., Jamar, F., Donckier, J., Hainaut, P., De Coster, P., Beckers, C., & Pauwels, S. (1996). Increased uptake of indium-111 pentetreotide up to 10 years after external thoracic irradiation: report of two cases. European journal of nuclear medicine, 23(6), 723-726. https://hdl.handle.net/2078.5/42514 (Original work published 1996)