The Clinical Utility of Liquid Biopsy by Digital Droplet PCR in Patients with Advanced NSCLC [P34.06]

Lamberts, Virginie;Aldea, Mihaela;Mezquita, Laura;Jovelet, Cécile;Planchard, David;et.al.
(2021) 2020 World Conference on Lung Cancer — Location: Virtual (28.January.2021)

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Authors
  • Lamberts, Virginie
    Author
  • Aldea, Mihaela
    Author
  • Mezquita, Laura
    Author
  • Jovelet, Cécile
    Author
  • Author
  • Planchard, David
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Abstract
INTRODUCTION : EGFR mutations occur in 15% of Caucasian and up to 50% of Asian patients with advanced NSCLC. Tissue genomic profiling is the gold standard but the liquid biopsy is a good surrogate of the tissue for molecular diagnosis. The digital droplet PCR (ddPCR) is a rapid and low-cost liquid biopsy technique for genomic analyses. We aimed to evaluate the clinical utility of the ddPCR for genomic profiling of advanced NSCLC with EGFR mutations. [...]
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Citations

Lamberts, V., Aldea, M., Mezquita, L., Jovelet, C., Vasseur, D., Aboubakar Nana, F., Remon, J., Rouleau, E., Lacroix, L., Ngo Camus, M., Nicotra, C., Naltet, C., Lavaud, P., Gazzah, A., Besse, B., & Planchard, D. (2021). The Clinical Utility of Liquid Biopsy by Digital Droplet PCR in Patients with Advanced NSCLC [P34.06]. Journal of Thoracic Oncology, 16(3), S417. https://doi.org/10.1016/j.jtho.2021.01.697 (Original work published 2021)