INTRODUCTION : EGFR mutations occur in 15% of Caucasian and up to 50% of Asian patients with advanced NSCLC. Tissue genomic profiling is the gold standard but the liquid biopsy is a good surrogate of the tissue for molecular diagnosis. The digital droplet PCR (ddPCR) is a rapid and low-cost liquid biopsy technique for genomic analyses. We aimed to evaluate the clinical utility of the ddPCR for genomic profiling of advanced NSCLC with EGFR mutations. [...]
Lamberts, V., Aldea, M., Mezquita, L., Jovelet, C., Vasseur, D., Aboubakar Nana, F., Remon, J., Rouleau, E., Lacroix, L., Ngo Camus, M., Nicotra, C., Naltet, C., Lavaud, P., Gazzah, A., Besse, B., & Planchard, D. (2021). The Clinical Utility of Liquid Biopsy by Digital Droplet PCR in Patients with Advanced NSCLC [P34.06]. Journal of Thoracic Oncology, 16(3), S417. https://doi.org/10.1016/j.jtho.2021.01.697 (Original work published 2021)