HIV-2: A summary of present standard of care and treatment options for HIV-2 infected individuals living in Western Europe.
(2021) Clinical infectious diseases — Vol. 72, n° 3, p. 503-509 (2021)
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- Abstract
- HIV-2 infection is endemic in some countries in West Africa. Due to the lower prevalence in industrialized countries, there is limited experience and knowledge on management of HIV-2 infected individuals in Europe. Compared to HIV-1, there are differential characteristics of HIV-2 regarding diagnostic procedures, clinical course and, most importantly, antiretroviral therapy. We integrated the published literature on HIV-2 (studies and reports on epidemiology, diagnostics, clinical course, treatment) as well as expert experience in diagnosing and clinical care of HIV-2 infected to provide recommendations for a present standard of medical care of HIV- infected in Western European countries, including an overview of strategies for diagnosis, monitoring and treatment, with suggestions for effective drug combinations for first- and second line treatment, post-exposure prophylaxis and prevention of mother-to-child transmission as well as listings of mutations related to HIV-2 drug resistance- and CCR5/CRCX4 co-receptor tropism.
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Citations
Berzow, D., Descamps, D., Obermeier, M., Charpentier, C., Kaiser, R., Guertler, L., Eberle, J., Wensing, A., Sierra, S., Ruelle, J., Gomes, P., Mansinho, K., Taylor, N., Jensen, B., Döring, M., Stürmer, M., Rockstroh, J., & Camacho, R. (2021). HIV-2: A summary of present standard of care and treatment options for HIV-2 infected individuals living in Western Europe. Clinical infectious diseases, 72(3), 503-509. https://doi.org/10.1093/cid/ciaa275 (Original work published 2021)