Fatal community-acquired ribotype 002 Clostridium difficile bacteremia.

Dauby, Nicolas;Libois, Agnès;Van Broeck, Johan;Delmée, Michel;Martiny, Delphine;et.al.
(2017) Anaerobe — Vol. 44, p. 1-2 (2017)

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Authors
  • Dauby, Nicolas
    Author
  • Libois, Agnès
    Author
  • Van Broeck, JohanUCLouvain
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  • Author
  • Martiny, Delphine
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Abstract
Extra-colonic infections, and especially bacteremia, are infrequent manifestations of Clostridium difficile infection. C. difficile bacteremia is generally health-care associated and polymicrobial. We report the case of a patient on hunger strike that presented a C. difficile colitis and mono-microbial bacteremia on its admission to the hospital. Multilocus variable number tandem repeat analysis of stool and blood isolates indicated clonality. The strain was characterized as a ribotype 002, an emerging ribotype previously associated with high fatality rate. The patient received treatment by intra-venous amoxicillin-clavulanate and oral vancomycin but eventually died on the seventh day of admission with concomitant pneumonia and pulmonary embolism.
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Dauby, N., Libois, A., Van Broeck, J., Delmée, M., Vandenberg, O., & Martiny, D. (2017). Fatal community-acquired ribotype 002 Clostridium difficile bacteremia. Anaerobe, 44, 1-2. https://doi.org/10.1016/j.anaerobe.2016.12.013 (Original work published 2017)