Diagnosis and Management of Metastatic Prostate Cancer
(2014) Prostate Cancer: Diagnosis and clinical management — ISBN: [978-111834737-9], p. 245-264, published
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- Abstract
- With the widespread use of prostate-specific antigen (PSA) testing, metastatic prostate cancer is diagnosed less frequently. Consequently, not every newly diagnosed patient needs an imaging workshop. In patients with high-risk disease, the standard algorithm based on technetium bone scanning and computed tomography has clear limitations. In near future, magnetic resonance imaging and positron emission tomography should emerge as upfront imaging techniques. Androgen deprivation therapy remains the cornerstone treatment modality of metastatic prostate cancer. Despite many years of intensive use, many questions remain open, including the optimal timing of therapy, the optimal modality, and the role of intermittent treatment. Future strategies will include bone-targeted therapies, local treatment of oligo-metastatic disease, and combination of systemic therapies.
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Citations
Tombal, B., & Lecouvet, F. (2014). Diagnosis and Management of Metastatic Prostate Cancer. In Ashutosh K. Tewari, Peter Whelan, John D. Graham (ed.), Prostate Cancer: Diagnosis and clinical management (p. p. 245-264). Wiley Blackwell. https://doi.org/10.1002/9781118347379.ch13