Fragmentation of the QRS complex: the latest electrocardiographic craze?

Brohet, Christian
(2019) Acta Cardiologica : an international journal of cardiology — Vol. 74, n° 3, p. 185-187 (2019)

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  • Brohet, ChristianUCLouvain
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Abstract
The wording « fragmentation of the QRS complex » or « fragmented QRS » (fQRS) indicates the presence of high frequency potentials (spikes) inside the QRS complex. The term was first coined in 1973 in the report of an experimental study of canine hearts where coronary occlusion provoked the appearance of fragmented electrograms which were a source of reentrant activity [1]. Previously, it had already been suggested that a high frequency « notching » of the QRS complex could be a marker for cardiac structural diseases causing biventricular enlargement [2]. The appearance of fQRS can be provoked by any condition interfering with the normally homogeneous depolarisation process within the myocardium and leading to local conduction slowing, e.g. ischemia, scar, fibrosis, myofiber disarray, inflammation, and microvascular abnormality.
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Brohet, C. (2019). Fragmentation of the QRS complex: the latest electrocardiographic craze? Acta Cardiologica : an international journal of cardiology, 74(3), 185-187. https://doi.org/10.1080/00015385.2019.1600827 (Original work published 2019)