Subzonal Insemination - a Prospective Randomized Study in Patients With Abnormal Sperm Morphology
(1993) Fertility and Sterility — Vol. 60, n° 2, p. 307-313 (1993)
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- Abstract
- Objective: To evaluate in a prospective randomized study the outcome of subzonal insemination (SUZI) in patients with male subfertility. Design: In a period of 7 months, 48 patients underwent IVF treatment for male subfertility reasons. Normal insemination and SUZI were performed on sibling oocytes. Patients were divided into three groups depending on the sperm morphology (strict criteria): group 1, 10% to 14%; group 2, 5% to 10%; group 3, 0% to 5%. Setting: Private fertility center in Leuven, Belgium. Main Outcome Measures: The fertilization rates, cleavage rates, implantation rates, and pregnancy rates between the normally inseminated and the SUZI-treated group were compared. Results: The fertilization rate with SUZI was significantly higher (32%) than after normal insemination (7%). The difference was striking in groups 2 and 3 (35% and 33% versus 11% and 4%). Conclusion: This study indicates that SUZI increases the fertility outcome in patients with male subfertility and that there is a marked difference in fertilization rate when morphology, using strict criteria, is <10%.
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Gordts, S., Garcia, G., Vercruyssen, M., Roziers, P., Campo, R., & Swinnen, K. (1993). Subzonal Insemination - a Prospective Randomized Study in Patients With Abnormal Sperm Morphology. Fertility and Sterility, 60(2), 307-313. https://hdl.handle.net/2078.5/146902 (Original work published 1993)