(en) Both KDIGO and KDOQI guidelines state that ‘a donor candidate with atherosclerotic renal artery disease or fibromuscular dysplasia (FMD) involving the orifices of both renal arteries should not donate’ a kidney. However, the meaning of ‘orifices’ for FMD is somewhat uncertain as multifocal FMD mostly affects mid-to-distal segments of renal arteries. Furthermore, this recommendation is ‘not graded’ because of the lack of robust evidence in the literature. Consequently, nephrologists and transplant surgeons are often faced with a dilemma when counselling potential kidney donors in whom FMD has been found incidentally on pre-surgery screening tests or peri-operatively. As a result, practices across the world vary, with donation less likely to proceed unless FMD was undetected prior to surgery, the degree of FMD is deemed mild or as a last resort. [...]
Chrysochou, C., Devresse, A., Kanaan, N., & Persu, A. (2021). Kidney donors with fibromuscular dysplasia, is it time to open the doors? Nephrology, dialysis, transplantation, 36(8), 1365-1368. https://doi.org/10.1093/ndt/gfab181 (Original work published 2021)