Kidney donors with fibromuscular dysplasia, is it time to open the doors?

Chrysochou, Constantina;Devresse, Arnaud;Kanaan, Nada;Persu, Alexandre
(2021) Nephrology, dialysis, transplantation — Vol. 36, n° 8, p. 1365-1368 (2021)

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Abstract
(en) Both KDIGO and KDOQI guidelines state that ‘a donor candidate with atherosclerotic renal artery disease or fibromuscular dysplasia (FMD) involving the orifices of both renal arteries should not donate’ a kidney. However, the meaning of ‘orifices’ for FMD is somewhat uncertain as multifocal FMD mostly affects mid-to-distal segments of renal arteries. Furthermore, this recommendation is ‘not graded’ because of the lack of robust evidence in the literature. Consequently, nephrologists and transplant surgeons are often faced with a dilemma when counselling potential kidney donors in whom FMD has been found incidentally on pre-surgery screening tests or peri-operatively. As a result, practices across the world vary, with donation less likely to proceed unless FMD was undetected prior to surgery, the degree of FMD is deemed mild or as a last resort. [...]
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Chrysochou, C., Devresse, A., Kanaan, N., & Persu, A. (2021). Kidney donors with fibromuscular dysplasia, is it time to open the doors? Nephrology, dialysis, transplantation, 36(8), 1365-1368. https://doi.org/10.1093/ndt/gfab181 (Original work published 2021)