Oral fingolimod or intramuscular interferon for relapsing multiple sclerosis.

Cohen, Jeffrey A;Barkhof, Frederik;Comi, Giancarlo;Hartung, Hans-Peter;Sindic, Christian;et.al.
(2010) New England Journal of Medicine — Vol. 362, n° 5, p. 402-415 (2010)

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Authors
  • Cohen, Jeffrey A
    Author
  • Barkhof, Frederik
    Author
  • Comi, Giancarlo
    Author
  • Hartung, Hans-Peter
    Author
  • Sindic, ChristianUCLouvain
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Abstract
This trial showed the superior efficacy of oral fingolimod with respect to relapse rates and MRI outcomes in patients with multiple sclerosis, as compared with intramuscular interferon beta-1a. Longer studies are needed to assess the safety and efficacy of treatment beyond 1 year. (ClinicalTrials.gov number, NCT00340834.)
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Citations

Cohen, J. A., Barkhof, F., Comi, G., Hartung, H.-P., Khatri, B. O., Montalban, X., Pelletier, J., Capra, R., Gallo, P., Izquierdo, G., Tiel-Wilck, K., de Vera, A., Jin, J., Stites, T., Wu, S., Aradhye, S., Kappos, L., & Sindic, C. (2010). Oral fingolimod or intramuscular interferon for relapsing multiple sclerosis. New England Journal of Medicine, 362(5), 402-415. https://doi.org/10.1056/NEJMoa0907839 (Original work published 2010)