Les mécanismes chimiques de la radiostérilisation de médicaments solides

Tilquin, Bernard;Crucq, AS.
(1999) Conference on the Development and Current Problems in Radiation Chemistry (JECR-1998) — Location: BONASCRE(France) (21.June.1998)

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  • Tilquin, BernardUCLouvain
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  • Crucq, AS.
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Abstract
This paper is devoted to the chemical mechanisms associated with the radiosterilization of solid pharmaceuticals, Microbial tests and potency determinations proved the feasibility of the sterilization process. The literature about the radio-induced chemistry is very poor. Nevertheless, these are essential for the understanding of the process. This article deals with the actual hypotheses and the capability to predict the radio-induced degradation due to the radiosterilization process.
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Tilquin, B., & Crucq, AS. (1999). Les mécanismes chimiques de la radiostérilisation de médicaments solides. Journal de Chimie Physique, 96(1), 167-173. https://doi.org/10.1051/jcp:1999126 (Original work published 1999)