Advances in Platelet Function Testing-Light Transmission Aggregometry and Beyond.

Le Blanc, Jessica;Mullier, François;Vayne, Caroline;Lordkipanidzé, Marie
(2020) Journal of Clinical Medicine — Vol. 9, n° 8, p. E2636 [1-18] (2020)

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  • Le Blanc, Jessicaorcid-logo
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  • Vayne, Carolineorcid-logo
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  • Lordkipanidzé, Marieorcid-logo
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Abstract
Platelet function testing is essential for the diagnosis of hemostasis disorders. While there are many methods used to test platelet function for research purposes, standardization is often lacking, limiting their use in clinical practice. Light transmission aggregometry has been the gold standard for over 60 years, with inherent challenges of working with live dynamic cells in specialized laboratories with independent protocols. In recent years, standardization efforts have brought forward fully automated systems that could lead to more widespread use. Additionally, new technical approaches appear promising for the future of specialized hematology laboratories. This review presents developments in platelet function testing for clinical applications.
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Citations

Le Blanc, J., Mullier, F., Vayne, C., & Lordkipanidzé, M. (2020). Advances in Platelet Function Testing-Light Transmission Aggregometry and Beyond. Journal of Clinical Medicine, 9(8), E2636 [1-18]. https://doi.org/10.3390/jcm9082636 (Original work published 2020)