The European NEAT program: an integrated approach using acamprosate and psychosocial support for the prevention of relapse in alcohol-dependent patients with a statistical modeling of therapy success prediction.

Pelc, I;Landron, Frédéric;Fuchs, JW;Fischer, L.;Ansoms, C;et.al.
(2003) Alcoholism: Clinical and Experimental Research — Vol. 26 (2003)

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Authors
  • Pelc, I
    Author
  • Landron, Frédéric
    Author
  • Fuchs, JW
    Author
  • Fischer, L.
    Author
  • Ansoms, C
    Author
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Abstract
(en) Multicenter, prospective study in five European countries to observe outcome in alcohol misusers treated for 24 weeks with acamprosate and various psychosocial support techniques, within the setting of standard patient care. 1289 patients were recruited,543 (42.1%)patients were observed for the full 24-week period. The overall proportion of cumulative abstinence days was 0.48. Multiple physical and psychiatric comorbidities and a history of drug addiction were negatively correlated with outcome, as were, to a lesser extent, multiple previous episodes of detoxification, unemployment, and living alone. Older age and stable employment were positively associated with outcome. The difference in the unadjusted proportion of cumulative abstinence days between countries was significant (p< 0.001). Overall, outcome was not influenced by the nature of the psychosocial support provided. Adverse events were generally mild, with gastrointestinal disorders, which occurred in 21.5% of patients.
Affiliations
  • Louvain School of Management

Citations

Pelc, I., Landron, F., Fuchs, J., Fischer, L., Lehert, P., & Ansoms, C. (2003). The European NEAT program: an integrated approach using acamprosate and psychosocial support for the prevention of relapse in alcohol-dependent patients with a statistical modeling of therapy success prediction. Alcoholism: Clinical and Experimental Research, 26. https://hdl.handle.net/2078.5/128551 (Original work published 2003)