Lipid peroxidation, stellate cell activation and hepatic fibrogenesis in a rat model of chronic steatohepatitis.
(2003) Journal of Hepatology — Vol. 39, n° 5, p. 756-764 (2003)
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- Abstract
- The MCD model of 'fibrosing steatohepatitis' replicates the histologic features of human steatohepatitis, and the sequence of steatosis, inflammatory cell injury and fibrogenesis. The temporal sequence is consistent with a concept for involvement of oxidative injury in inflammatory recruitment and pathogenesis of hepatic fibrogenesis.
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Citations
George, J., Pera, N., Phung, N., Leclercq, I., Yun Hou, J., & Farrell, G. (2003). Lipid peroxidation, stellate cell activation and hepatic fibrogenesis in a rat model of chronic steatohepatitis. Journal of Hepatology, 39(5), 756-764. https://doi.org/10.1016/S0168-8278(03)00376-3 (Original work published 2003)