Effect of hydroxy ethyl starch (HES) 130/0.4 on renal function and mortality one year after adult cardiac surgery : A single center retrospective study
(2017) Acta Anaesthesiologica Belgica — Vol. 68, n° 3, p. 73-79 (2017)
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- Abstract
- Hydroxyethyl starch (HES) adversely affect short-term survival and renal function of intensive care unit and possibly of surgical patients. We retrospectively investigated whether using HES as a pump prime and for intraoperative fluid therapy is associated with mortality and end-stage renal failure one year after adult cardiac surgery. Multivariable logistic regression was used to adjust for imbalanced characteristics between the two study groups. The primary outcome, a composite of end-stage renal failure or mortality during the first postoperative year was observed in 9.7% of patients who received HES and in 6.2% of patients treated with crystalloids only (Adjusted OR 1.05; 95%CI, 0.5-2; P = 0.9). These results suggest that using HES or balanced crystalloids as a pump prime and for intraoperative fluid therapy results in similar one-year outcomes but must be considered as preliminary given the limited statistical power of the study.
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SERVAIS, E., & et al. (2017). Effect of hydroxy ethyl starch (HES) 130/0.4 on renal function and mortality one year after adult cardiac surgery : A single center retrospective study. Acta Anaesthesiologica Belgica, 68(3), 73-79. https://hdl.handle.net/2078.5/61419 (Original work published 2017)