Design, synthesis and evaluation of serine protease inhibitor analogues
(2007) European Journal of Organic Chemistry — Vol. 2007, n° 18, p. 2977-2986 (2007)
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- Authors
- Abstract
- Recent efforts in the field of thrombin inhibitor research have focused on the identification of pyrazinone-containing compounds. In this manuscript we describe the synthesis of the new pyrazinones 12-36. All the targets were fully characterised and screened for serine protease inhibition. © Wiley-VCH Verlag GmbH & Co. KGaA, 2007.
- Affiliations
KU LEUVEN Department of Chemistry
Citations
Kamoune, L., De Borggraeve, W. M., Gielens, C., Voet, A., Robeyns, K., De Maeyer, M., Van Meervelt, L., Compernolle, F., & Hoornaert, G. (2007). Design, synthesis and evaluation of serine protease inhibitor analogues. European Journal of Organic Chemistry, 2007(18), 2977-2986. https://doi.org/10.1002/ejoc.200700180 (Original work published 2007)