Tinnitus following COVID-19 vaccination: report of three cases.

Parrino, Daniela;Frosolini, Andrea;Gallo, Chiara;De Siati, Romolo Daniele;de Filippis, Cosimo;et.al.
(2022) International Journal of Audiology — Vol. 61, n° 6, p. 526-529 (2022)

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Authors
  • Parrino, Danielaorcid-logo
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  • Frosolini, Andreaorcid-logo
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  • Gallo, Chiara
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  • de Filippis, Cosimoorcid-logo
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Abstract
OBJECTIVE: To ensure the safety and quality of vaccines, especially the newest RNA-vaccines against COVID-19, is one of the World Health Organization's current highest priorities. DESIGN: Case description. STUDY SAMPLE: We report three cases of sudden unilateral tinnitus following BNT162b2 mRNA-vaccine injection, which rapidly resolved in 2 out of 3 cases. RESULTS: The mechanism responsible for its development remains unclear. A hypersensitivity reaction with an abnormal autoimmune response or a vasculitic event may be implicated. CONCLUSIONS: Large-scale and well-designed studies are needed to improve surveillance of the COVID-19 vaccine and better define possible adverse reactions involving the cochleo-vestibular system and/or immunisation anxiety-related reactions.
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Citations

Parrino, D., Frosolini, A., Gallo, C., De Siati, R. D., Spinato, G., & de Filippis, C. (2022). Tinnitus following COVID-19 vaccination: report of three cases. International Journal of Audiology, 61(6), 526-529. https://doi.org/10.1080/14992027.2021.1931969 (Original work published 2022)