This study confirmed the safety and tolerability profile of peginterferon alfa-2a/ribavirin and identified patient subgroups at higher risk of dose reductions and discontinuations, thus allowing optimum management of AEs.
Lee, S. S., Roberts, S. K., Berak, H., Dusheiko, G. M., Harley, H. A., Gane, E. J., Husa, P., Horsmans, Y., Hadziyannis, S. J., Jenny Heathcote, E., Messinger, D., Tatsch, F., Han, K.-H., & Ferenci, P. (2012). Safety of peginterferon alfa-2a plus ribavirin in a large multinational cohort of chronic hepatitis C patients. Liver International, 32(8), 1270-1277. https://doi.org/10.1111/j.1478-3231.2012.02819.x (Original work published 2012)