Synthesis of novel cyclopropylic sulfones and sulfonamides acting as glucokinase activators

Heuser, S;Barrett, DG;Berg, M.;Bonnier, B;Weichert, AG;et.al.
(2006) Tetrahedron Letters — Vol. 47, n° 16, p. 2675-2678 (2006)

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Authors
  • Heuser, S
    Author
  • Barrett, DG
    Author
  • Berg, M.
    Author
  • Bonnier, B
    Author
  • Weichert, AG
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Abstract
A synthetic route towards cyclopropylic compounds, which act as glucokinase activators is described herein. The present synthesis gives easy and rapid access to a wide variety of either sulfones or sulfonamides starting from readily available late-stage intermediates. (c) 2006 Elsevier Ltd. All rights reserved.
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Heuser, S., Barrett, D., Berg, M., Bonnier, B., Kahl, A., De la Puente, M., Oram, N., Riedl, R., Roettig, U., Gil, G., Seger, E., Steggles, D., Wanner, J., & Weichert, A. (2006). Synthesis of novel cyclopropylic sulfones and sulfonamides acting as glucokinase activators. Tetrahedron Letters, 47(16), 2675-2678. https://doi.org/10.1016/j.tetlet.2006.02.110 (Original work published 2006)