Atteinte cérébrale au cours d’une maladie de Wegener : Central nervous system involvement in Wegener’s granulomatosis

Jouret, François;Noirhomme, Séverine;Grandin, Cécile;Lonneux, Max;Lefebvre, Chantal;et.al.
(2008) La Revue de médecine interne — Vol. 29, n° 11, p. 912-916 (2008)

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Authors
  • Jouret, FrançoisUCLouvain
    Author
  • Noirhomme, Séverine
    Author
  • Grandin, CécileUCLouvain
    Author
  • Lonneux, MaxUCLouvain
    Author
  • Godfraind, CatherineUCLouvain
    Author
  • Lambert, MichelUCLouvain
    Author
  • Lefebvre, ChantalUCLouvain
    Author
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Abstract
(en) Introduction : Wegener's granulomatosis (WG) is a systemic necrotizing vasculitis associated with c-ANCA antibodies. The involvement of the central nervous system in WG is uncommon and usually caused by in situ vasculitis, intracranial granuloma formation or contiguous invasion from extracranial sites. Case report : Here, we report on a tumour-like expansion of a severe nasosinusal WG into the brain, which was confirmed by brain biopsy examination. Conclusion : The positivity of positron emission tomography in our observation supports the potential role of such functional imaging in the staging, as well as in the follow-up of WG.
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Citations

Jouret, F., Noirhomme, S., Grandin, C., Lonneux, M., Godfraind, C., Lambert, M., & Lefebvre, C. (2008). Atteinte cérébrale au cours d’une maladie de Wegener : Central nervous system involvement in Wegener’s granulomatosis. La Revue de médecine interne, 29(11), 912-916. https://doi.org/10.1016/j.revmed.2008.04.003 (Original work published 2008)