Pitfalls in the detection of disseminated non-hematological tumor cells.
(2000) Annals of Oncology — Vol. 11, n° 7, p. 785-792 (2000)
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- Abstract
- There is not yet a consensus on the reliability of the methods that should be used for the detection of rare disseminated tumor cells from non-hematological malignancies. In this review, we will discuss the advantage and drawbacks of the classical approach of immunocytochemistry and the molecular detection by reverse transcriptase polymerase chain reaction (RT-PCR). The interpretation of the biological significance of circulating tumor cells and the pitfalls of the detection techniques are the main causes of discrepancy between the conclusions of different tumor-cell detection (TCD) studies.
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Goeminne, J. C., Guillaume, T., & Symann, M. (2000). Pitfalls in the detection of disseminated non-hematological tumor cells. Annals of Oncology, 11(7), 785-792. https://doi.org/10.1023/A:1008398228018 (Original work published 2000)