French‐Speaking Network of Pharmacogenetics (RNPGx) Recommendations for Gene Panel Analysis Through Genotyping or Sequencing in Pharmacogenetics

Picard, Nicolas;Ayme‐dietrich, Estelle;Quaranta, Sylvie;Adam‐de‐beaumais, Tiphaine;Haufroid, Vincent;et.al.
(2026) Fundamental and Clinical Pharmacology — Vol. 40, n° 1, p. / (2026)

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Authors
  • Picard, Nicolasorcid-logoDepartment of Pharmacology, Toxicology and Pharmacovigilance, Inserm 1248 P&T CHU Limoges Limoges France
    Author
  • Ayme‐dietrich, EstelleLaboratory of Neurocardiovascular Pharmacology and Toxicology, UR7296 University Hospitals of Strasbourg Strasbourg France
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  • Quaranta, SylvieLaboratory of Molecular Biology GEnOPé / Laboratory of Pharmacokinetic and Toxicology, Timone Hospital AP‐HM Marseille France
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  • Adam‐de‐beaumais, TiphaineDepartment of Children and Adolescents Oncology Gustave Roussy Villejuif France
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  • Haufroid, VincentUCLouvain
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  • et. al.
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Abstract
Background: The implementation of pharmacogenetics in clinical practice increasingly relies on multigene panels. Objectives: The objective of this study is to develop harmonized recommendations for the design and analytical implementation of multigene pharmacogenetic panels, defining clinically relevant genes and associated regions of interest (ROIs) based on evidence strength, therapeutic applicability, and compatibility with genotyping or sequencing technologies.
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Picard, N., Ayme‐dietrich, E., Quaranta, S., Adam‐de‐beaumais, T., Ait tayeb, A., Alarcan, H., Amor, D., Barthelemy, D., Sassi, M., Cunat, S., Daldoul, M., Delacour, H., Etienne‐grimaldi, M.-c., Fonrose, X., Hennart, B., Lebreton, L., Malard, S., Narjoz, C., Omezzine, A., et al. (2026). French‐Speaking Network of Pharmacogenetics (RNPGx) Recommendations for Gene Panel Analysis Through Genotyping or Sequencing in Pharmacogenetics. Fundamental and Clinical Pharmacology, 40(1), /. https://doi.org/10.1111/fcp.70068 (Original work published 2026)