Tc-99m Hmpao Single Photon-emission Computed-tomography Imaging in Transient Global Amnesia
(1992) Archives of Neurology — Vol. 49, n° 5, p. 543-546 (1992)
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- Abstract
- Five right-handed patients with pure transient global amnesia were evaluated with technetium-99m hexamethylpropyleneamine oxime single photon emission computed tomography after the amnesic attack. Independent of the interval between the procedure and the amnesic episode, single photon emission computed tomography demonstrated a decreased cerebral blood flow in the left temporal lobe in one patient and in the left parietotemporal region in three patients, with a more marked reduction in the temporal lobe. The remaining three patients were normal. A control single photon emission computed tomographic study was carried out in one patient 3 months after the amnesic attack and showed a left-sided persistent temporal hypoperfusion. These findings suggest that in some patients, transient global amnesia can be due to a vascular mechanism requiring strong investigations for vascular risk factors and appropriate treatment. During a follow-up period of 12 to 32 months, none of the patients with regional hypoperfusion suffered cerebrovascular events, suggesting that single photon emission computed tomography has no predictive value for further stroke.
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Laloux, P., Brichant, C., Cauwe, F., & De Coster, P. (1992). Tc-99m Hmpao Single Photon-emission Computed-tomography Imaging in Transient Global Amnesia. Archives of Neurology, 49(5), 543-546. https://hdl.handle.net/2078.5/68931 (Original work published 1992)