Comparison of two exercise testing protocols in patients with chronic fatigue syndrome

Nijs, Jo;Zwinnen, Kim;Meeusen, Romain;de Geus, Sebastiaan;De Meirleir, Kenny
(2007) Journal of Rehabilitation Research and Development — Vol. 44, n° 4, p. 553 (2007)

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  • Nijs, JoVUB
    Author
  • Zwinnen, KimVUB
    Author
  • Meeusen, RomainVUB
    Author
  • Author
  • De Meirleir, KennyVUB
    Author
Abstract
This study examined wh ether a linear exercise stress-testing protocol generated different peak exercise per- formance variables than a stepwise exercise testing protocol in patients with chronic fatigue syndrome (CFS). We conducted a comparative study with patients randomly allocated to one of two exercise testing protocols. Twenty-eight women with CFS completed two self-reported measures (the CFS Symptom List and the CFS Activities and Participation Questionnaire) and then performed until exhaustion either the linear or the step- wise exercise testing protocol with continuous monitoring of physiological variables (heart rate and oxygen uptake). At baseline, we found no significant differences in demographic features and health status between groups (p > 0.05). Based on ratio peak workload/peak oxygen uptake, mechanical effi- ciency was lower among the subjects performing the stepwise protocol ( p = 0.002). When we analyzed the mean linear regression slope values between oxygen uptake and workload from each subject’s minute-by-minute exercise data points, we found that mechanical efficiency was lower among the subjects performing the stepwise protocol ( p = 0.039). Apart from mechanical efficiency, we found no differences in exercise per- formance data between groups ( p > 0.05). Our results suggest that the difference between linear and stepwise exercise proto- cols cannot account for all discrepancies of previous studies on exercise performance data in women with CFS, but they do suggest that the nature of the exercise testing protocol influ- ences mechanical efficiency in these patients. Further study is warranted.
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Nijs, J., Zwinnen, K., Meeusen, R., de Geus, S., & De Meirleir, K. (2007). Comparison of two exercise testing protocols in patients with chronic fatigue syndrome. Journal of Rehabilitation Research and Development, 44(4), 553. https://doi.org/10.1682/jrrd.2006.12.0153 (Original work published 2007)