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EUGMS2020_Poster836_IHMratesinolderCOVID-19inpatients2copy.pdf
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Background: Little is known at the end of spring 2020 about in- hospital mortality (IHM) rates of older inpatients with COVID-19. Valid IHM rate calculations require a cohort study design with complete follow-up of all patients until hospital discharge. The aim of this study was to describe IHM rates in older patients (C 65 years) with COVID-19. Methods: Medical literature review from December 1, 2019 to June 17, 2020 of cohort studies including older patients (OP) with COVID- 19. The outcome was the patient’s vital status (death or alive) upon hospital discharge. Results: Twenty cohort studies selected and compared OP with the outcome at a certain hospital date (censoring bias). Four cohort studies completed the OP hospital follow-up, allowing calculation of the IHM rate. The IMH rate was 26.2% in 65 OP of the Pulmonary hospital in Wuhan [1], 34.5% in 55 OP of the Zhongnan hospital in Wuhan [2], 35.3% in 17 OP of the Dabieshan Medical Center in Huanggang [3] and 41.0%% in 117 OP of the Chelsea & Westminster hospital in London [4]. Pooling these four cohorts (710 COVID-19 inpatients), we calculated an average IHM rate of 35.4% [95% CI 29.6–41.3%] in the 254 OP, which was six times higher than the IHM rate of 5.9% [95% CI 3.6–8.2%] in the 456 younger patients. Conclusion: Few COVID-19 cohort studies which included older patients have reported the vital status of all patients at hospital dis- charge. Completed cohorts are deeply needed to determine the IHM rates in this high risk population.
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Mahiat, C., de Terwangne, C., De Brauwer, I., Henrard, S., & Boland, B. (2020). In-hospital mortality rates in older COVID-19 inpatients: a literature review. European Geriatric Medicine, 11(S1), 1-309. https://doi.org/10.1007/s41999-020-00428-6 (Original work published 2020)