Unconventional roles of lactate along the tumor and immune landscape.

Ippolito, Luigi;Sonveaux, Pierre;Chiarugi, Paola
(2022) Trends in Endocrinology and Metabolism — Vol. 33, n° 4, p. 231-235 (2022)

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Abstract
The tumor ecosystem evolves with dynamic interactions between cancer and normal cells, and nutrients have emerged as new regulators of cancer hallmarks. Lactate has climbed the rankings as a multifunctional molecule orchestrating many aspects of the disease onset and progression. Here, we patchwork and discuss the main recent findings conferred during the EMBO workshop titled 'Lactate: Unconventional Roles of a Nutrient Along the Tumor Landscape.'
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Ippolito, L., Sonveaux, P., & Chiarugi, P. (2022). Unconventional roles of lactate along the tumor and immune landscape. Trends in Endocrinology and Metabolism, 33(4), 231-235. https://doi.org/10.1016/j.tem.2022.01.005 (Original work published 2022)