Accumulation of Protoporphyrin Isomers-i and Isomers-iii, and Multiple Decarboxylation Products of Uroporphyrin in a Case of Porphyria in a Slaughtered Pig

Roels, Sarah;Hassoun, A.;Hoorens, J.
(1995) Journal of Veterinary Medicine. Series A — Vol. 42, n° 2, p. 145-151 (1995)

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  • Roels, SarahUCLouvain
    Author
  • Hassoun, A.
    Author
  • Hoorens, J.
    Author
Abstract
Pathological and biochemical examinations were made on tissues from a case of porphyria in a slaughtered pig. Bones, kidneys, teeth and lymph nodes showed a mahogany discoloration. Histologically, the pigment was negative on staining for iron (Gomori) and showed a strong red-orange fluorescence under UV light proving it to be prophyrin. Biochemical studies on the kidney, lymph nodes, bone and bone marrow revealed a 'mixed' erythropoietic protoporphyria-coproporphyria. This indicates that the case presented probably represented both a uroporphyrinogen decarboxylase and uroporphyrinogen-III-cosynthase dysfunction.
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Roels, S., Hassoun, A., & Hoorens, J. (1995). Accumulation of Protoporphyrin Isomers-i and Isomers-iii, and Multiple Decarboxylation Products of Uroporphyrin in a Case of Porphyria in a Slaughtered Pig. Journal of Veterinary Medicine. Series A, 42(2), 145-151. https://hdl.handle.net/2078.5/45594 (Original work published 1995)