Amoebae as potential environmental hosts for Mycobacterium ulcerans and other mycobacteria, but doubtful actors in Buruli ulcer epidemiology.

Gryseels, Sophie;Amissah, Diana;Durnez, Lies;Vandelannoote, Koen;Eddyani, Miriam;et.al.
(2012) PLoS Neglected Tropical Diseases — Vol. 6, n° 8, p. e1764 (2012)

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Authors
  • Gryseels, Sophie
    Author
  • Amissah, Diana
    Author
  • Durnez, Lies
    Author
  • Vandelannoote, Koen
    Author
  • De Jonckheere, JohanUCLouvain
    Author
  • Eddyani, Miriam
    Author
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Abstract
This is the first report of experimental infection of amoebae with M. ulcerans and of the detection of the marker IS2404 in amoeba cultures isolated from the environment. We conclude that amoeba are potential natural hosts for M. ulcerans, yet remain sceptical about their implication in the transmission of M. ulcerans to humans and their importance in the epidemiology of Buruli ulcer.
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Citations

Gryseels, S., Amissah, D., Durnez, L., Vandelannoote, K., Leirs, H., De Jonckheere, J., Silva, M. T., Portaels, F., Ablordey, A., & Eddyani, M. (2012). Amoebae as potential environmental hosts for Mycobacterium ulcerans and other mycobacteria, but doubtful actors in Buruli ulcer epidemiology. PLoS Neglected Tropical Diseases, 6(8), e1764. https://doi.org/10.1371/journal.pntd.0001764 (Original work published 2012)