Pharmacological Modulation By Cetirizine and Ebastine of the Cutaneous Reactivity To Histamine

Rivest, J.;Despontin, K.;Ghys, L.;Rihoux, JP.;Lachapelle, Jean-Marie
(1991) Dermatologica — Vol. 183, n° 3, p. 208-211 (1991)

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Authors
  • Rivest, J.
    Author
  • Despontin, K.
    Author
  • Ghys, L.
    Author
  • Rihoux, JP.
    Author
  • Lachapelle, Jean-MarieUCLouvain
    Author
Abstract
The peripheral H-1-inhibition effects of cetirizine 10 mg and ebastine 10 mg were compared at the skin level after single oral administration. The study was performed in 9 healthy subjects under double-blind randomized crossover conditions. Both drugs were significantly effective up to 24 h. The suppressive effect of cetirizine was significantly more rapid and more marked.
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Rivest, J., Despontin, K., Ghys, L., Rihoux, JP., & Lachapelle, J.-M. (1991). Pharmacological Modulation By Cetirizine and Ebastine of the Cutaneous Reactivity To Histamine. Dermatologica, 183(3), 208-211. https://doi.org/10.1159/000247671 (Original work published 1991)