Antifungal lock therapy with combined 70% ethanol and micafungin in a critically ill infant.
(2014) The Pediatric infectious disease journal — Vol. 33, n° 4, p. 419-420 (2014)
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- Authors
- Abstract
- So-called lock therapy, consisting of high concentrations of antimicrobials instilled into the lumen of the catheter, has been suggested avoid central venous catheter removal during fungal infection. We report a baby who developed catheter-related candidemia. Systemic antifungal treatment did not resolve the candidemia. Lock therapy with 0.3 mL of ethanol 70% and micafungin sodium 5 mg/L was added to the therapy, and blood cultures became sterile.
- Affiliations
Bambino Gesù Children’s Hospital – (Italy) Roma Department of Medical and Surgical Neonatology
Citations
Piersigilli, F., Auriti, C., Bersani, I., Goffredo, B., Bianco, G., Savarese, I., & Dotta, A. (2014). Antifungal lock therapy with combined 70% ethanol and micafungin in a critically ill infant. The Pediatric infectious disease journal, 33(4), 419-420. https://doi.org/10.1097/INF.0000000000000116 (Original work published 2014)