Although Starzl designed in the 1960’s liver transplantation (LT) to treat unresectable primary and also secondary liver tumors, transplantation still occupies a (too) small place in the respective therapeutic algorithms. Due to the lack of (any) selection criteria, the concept of transplantation became rapidly challenged because of the prohibitively high incidence of tumor recurrence. Not surprisingly, the “oncological pendulum” reversed in the nineties and moved the indication for LT from large multifocal lesions to a more limited tumor burden. In fact the paradigm changed towards transplanting the resectable and resecting the “untransplantable” cancer. [...]
Lerut, J. (2024). Liver transplantation and liver resection as alternative treatments for primary hepatobiliary and secondary liver tumors: Competitors or allies? Hepatobiliary & Pancreatic Diseases International, 23(2), 111-116. https://doi.org/10.1016/j.hbpd.2023.12.001 (Original work published 2024)