A generic cycling hypoxia-derived prognostic gene signature: application to breast cancer profiling.

Boidot, Romain;Branders, Samuel;Helleputte, Thibault;Illan Rubio, Laila;Feron, Olivier;et.al.
(2014) OncoTarget — Vol. 5, n° 16, p. 6947-6963 (2014)

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Authors
  • Boidot, Romain
    Author
  • Branders, SamuelUCLouvain
    Author
  • Helleputte, ThibaultUCLouvain
    Author
  • Illan Rubio, LailaUCLouvain
    Author
  • Dupont, PierreUCLouvain
    Author
  • Feron, Olivierorcid-logoUCLouvain
    Author
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Abstract
Temporal and local fluctuations in O2 in tumors require adaptive mechanisms to support cancer cell survival and proliferation. The transcriptome associated with cycling hypoxia (CycHyp) could thus represent a prognostic biomarker of cancer progression.
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Boidot, R., Branders, S., Helleputte, T., Illan Rubio, L., Dupont, P., & Feron, O. (2014). A generic cycling hypoxia-derived prognostic gene signature: application to breast cancer profiling. OncoTarget, 5(16), 6947-6963. https://hdl.handle.net/2078.5/254353 (Original work published 2014)