Predictive value of serum alkaline DNase activity variations in treatment of head and neck cancer.
(1990) Acta Oncologica — Vol. 29, n° 2, p. 163-166 (1990)
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- Abstract
- The aim of this study was to evaluate the variation in serum alkaline DNase activity (SADA) as a means of therapeutic monitoring in patients with head and neck cancer. Blood samples from 40 patients were collected before, during, and some weeks up to months after therapy. A decrease in SADA during treatment was usually associated with a primary clinical response, while no decrease indicated non-response to therapy. In patients with complete tumor regression the initial decrease of SADA was usually followed by an increase exceeding the initial level. A similar increase was not observed in patients with tumor progression.
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Economidou-Karaoglou, A., Deckers, C., Roberfroid, M., Opsomer, M., Lans, M., & Taper, H. (1990). Predictive value of serum alkaline DNase activity variations in treatment of head and neck cancer. Acta Oncologica, 29(2), 163-166. https://hdl.handle.net/2078.5/137921 (Original work published 1990)