Use of early tumor shrinkage to predict long-term outcome in metastatic colorectal cancer treated with cetuximab.

Piessevaux, Hubert;Buyse, Marc;Schlichting, Michael;Van Cutsem, Eric;Tejpar, Sabine;et.al.
(2013) Journal of Clinical Oncology — Vol. 31, n° 30, p. 3764-3775 (2013)

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  • Buyse, Marc
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  • Schlichting, Michael
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  • Van Cutsem, Eric
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  • Tejpar, Sabine
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Abstract
ETS was significantly associated with long-term outcome in patients with KRAS wild-type mCRC treated first-line with chemotherapy plus cetuximab. Validation in prospective trials is required to assess the value of this on-treatment marker in the clinical decision-making process.
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Piessevaux, H., Buyse, M., Schlichting, M., Van Cutsem, E., Bokemeyer, C., Heeger, S., & Tejpar, S. (2013). Use of early tumor shrinkage to predict long-term outcome in metastatic colorectal cancer treated with cetuximab. Journal of Clinical Oncology, 31(30), 3764-3775. https://doi.org/10.1200/JCO.2012.42.8532 (Original work published 2013)