Exploring different preservation strategies in a pig kidney DCD autotransplant model
(2020)
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Details
- Authors
- Supervisors
- Mourad, Michel
- Abstract
- Dynamic preservation strategies are currently reintroduced in kidney transplantation to recondition/repair the organ with the aim to decrease ischemia-reperfusion injury and to improve early and late allograft function. In addition, transplantability measured by biomarkers or flow dynamics during and after machine perfusion is more feasible compared with static cold storage preservation. This work evaluates the optimal start time, temperature, oxygen concentration and oxygen administration technique during ex vivo machine perfusion in a porcine kidney donation after circulatory death (DCD) autotransplant model to decrease ischemia-reperfusion injury and subsequently improve early kidney graft function.
- Affiliations
Citations
Darius, T. (2020). Exploring different preservation strategies in a pig kidney DCD autotransplant model. https://hdl.handle.net/2078.5/31040