Characteristics, practices, and outcomes in a Belgian cohort of incident home hemodialysis patients: A 6-year experience.

Vô, Bernard;Anthonissen, Blaise;Verger, Christian;Jadoul, Michel;Goffin, Eric;et.al.
(2022) Hemodialysis International — Vol. 26, n° 3, p. 295-307 (2022)

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Authors
  • Vô, BernardUCLouvain
    Author
  • Anthonissen, BlaiseUCLouvain
    Author
  • Verger, Christianorcid-logo
    Author
  • Jadoul, MichelUCLouvain
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  • Goffin, EricUCLouvain
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Abstract
(en) BACKGROUND: Home hemodialysis (HHD) remains underused in patients with kidney failure. Current literature on HHD mostly originates from non-European countries, making generalization difficult. The present study describes patients' profile and practice patterns from a Belgian HHD center, and assesses patient and technique survival and complications associated with HHD. METHODS: We analyzed data from all our incident patients during a 6-year period. The patient's characteristics were summarized using descriptive statistics. Transition to another therapeutic modality, estimated using a risk model with death and transplantation as competing events, episodes of respite cares and hospitalizations, and access complications were analyzed. RESULTS: Eighty patients (mean age: 47 years; male: 64%) met the inclusion criteria. Fifty-one percent of patients initiated dialysis with a central venous catheter (CVC) and 96% were not assisted. Arterio-venous fistula (AVF) cannulation was performed using buttonhole technique. Standard-frequent HD (47%) and short-frequent low-flow dialysate HD (34%) were mostly used at HHD initiation. Cumulative incidences of technique failure and death were 15%, 24%, and 32% at 1, 2, and 5 years. Incidence rates for respite dialysis and hospitalizations were 2.39 and 0.54 per patient-year of HHD. In comparison with AVF, incidence rate ratios of overall access complications and access-related infections for CVC were 4.3 (95% CI: 3.1-6, p < 0.01) and 4.4 (95% CI: 2.1-10, p < 0.01), respectively. Buttonhole cannulation was complicated by 0.26 (95% CI: 0.15-0.46) infections per 1000 AVF-days. CONCLUSIONS: This present study provides important information about patient's profile and practice patterns and safety in a cohort of 80 incident Belgian HHD patients, with encouraging techniques and patient survival.
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Citations

Vô, B., Anthonissen, B., Verger, C., Jadoul, M., Morelle, J., & Goffin, E. (2022). Characteristics, practices, and outcomes in a Belgian cohort of incident home hemodialysis patients: A 6-year experience. Hemodialysis International, 26(3), 295-307. https://doi.org/10.1111/hdi.13014 (Original work published 2022)