Method and device for high sensitivity and quantitative detection of chemical/biological molecules

Demeersman, Benoit;Godfroid, Edmond;Jacquet, Alain;Prévot, Pierre-Paul;Blondeau, Françoise;et.al.
(2009)

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Authors
  • Demeersman, BenoitUCLouvain
    Inventor
  • Godfroid, Edmond
    Inventor
  • Jacquet, Alain
    Inventor
  • Prévot, Pierre-Paul
    Inventor
  • Tang, XiaohuiUCLouvain
    Inventor
  • Demoustier, SophieUCLouvain
    Inventor
  • Jonas, Alainorcid-logoUCLouvain
    Inventor
  • Bayot, VincentUCLouvain
    Inventor
  • Nysten, Bernardorcid-logoUCLouvain
    Inventor
  • Blondeau, FrançoiseUCLouvain
    Inventor
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Abstract
A sensor for detecting the presence of predetermined chemical/biological molecules, the sensor having a MOSFET device (2,3,6,7,9,10,12,13), the gate having an array of nanoscale fingers (6,7), and on fingers or in spaces between the fingers, chemical/biological receptor molecules (15) suitable for selectively binding with the predetermined chemical/biological molecules, the sensor also having circuitry (4,5,11,12 ) for measuring a change in a change in drain current of the FET caused by the predetermined chemical/biological molecules becoming bound to the receptor molecules. Sensitivity and reliability can be increased compared to capacitive sensors.
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Demeersman, B., Godfroid, E., Jacquet, A., Prévot, P.-P., Tang, X., Demoustier, S., Jonas, A., Bayot, V., Nysten, B., & Blondeau, F. (2009). Method and device for high sensitivity and quantitative detection of chemical/biological molecules (Patent No. EP2017609). https://hdl.handle.net/2078.5/270331