Left extended hepatectomy for a metastatic gastrointestinal stromal tumor after a disease-free interval of 17 years: report of a case.
(2007) Surgery Today : the Japanese journal of surgery — Vol. 37, n° 1, p. 70-73 (2007)
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- Authors
- Abstract
- Gastrointestinal stromal tumors (GISTs), although rare, are frequently diagnosed with liver metastasis. These metastatic GISTs are poorly responsive to conventional chemotherapy; however, recent studies report improved survival after complete surgical resection of liver metastases. On the other hand, few reports describe the treatment of delayed liver metastasis after resection of a primary GIST. We report the case of a 55-year-old woman found to have liver metastasis from a GIST after a 17-year disease-free interval. The patient underwent a left extended hepatectomy for a complete resection of the metastatic GIST and is alive and well 30 months later. To our knowledge, this is the longest disease-free interval reported in the literature, and emphasizes the importance of considering late metastasis when evaluating patients with a history of GIST. Thus, surgical resection of delayed liver metastasis from a GIST should be considered as primary therapy.
- Affiliations
Keck School of Medicine, University of Southern California, University Hospital, Los Angeles (USA) Division of Hepatobiliary/Pancreatic Surgery and Abdominal Organ Transplantation
Citations
Matsuoka, L., Stapfer, M., Mateo, R., Jabbour, N., Naing, W., Selby, R., & Gagandeep, S. (2007). Left extended hepatectomy for a metastatic gastrointestinal stromal tumor after a disease-free interval of 17 years: report of a case. Surgery Today : the Japanese journal of surgery, 37(1), 70-73. https://doi.org/10.1007/s00595-006-3338-y (Original work published 2007)